Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669890 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL28866775 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL4669888 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL3369452 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL4669921 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL3780597 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL2897972 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL1221172 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7264173 | 0.99 | ACE (0.59) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL11041388 | 0.99 | ACE (0.59) | ACELMNAABCB11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878432-A | Method for preparing N- [1- (S) -ethoxycarbonyl-3-phenylpropyl ] -L-alanine by continuous flow method | 浙江昌明药业有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-113549126-B | Preparation method of ramipril | 鲁南制药集团股份有限公司 | 2024-04-19 | — | — | CN | claimed |
| EP-3489215-B1 | PROCESS FOR PRODUCING ORGANIC COMPOUND | KANEKA CORP (JP) | 2023-12-20 | — | — | EP | claimed |
| CN-113024632-B | Preparation method of imidapril hydrochloride | 山东中健康桥制药有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-109021064-B | Preparation method of enalapril maleate | 扬子江药业集团有限公司 | 2021-11-09 | — | — | CN | claimed |
| CN-113549126-A | Preparation method of ramipril | 鲁南制药集团股份有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-109689611-B | Method for producing organic compound | 株式会社钟化 | 2021-09-28 | — | — | CN | claimed |
| CN-105713068-B | Method for preparing imidapril key intermediate and derivative thereof | 湖南九典制药股份有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-108147973-B | Preparation method of N- [1- (S) -ethoxycarbonyl-3-phenylpropyl ] -L-alanine | 凯莱英医药集团（天津）股份有限公司 | 2021-04-06 | — | — | CN | claimed |
| US-10781193-B2 | Process for producing organic compound | KANEKA CORPORATION (JP) | 2020-09-22 | — | — | US | claimed |
| US-5359086-A | Process for preparing alkyl-L-alanyl-L-proline derivatives | KRKA, PHARMACEUTICAL & CHEMICAL WORKS (SI) | 1994-10-25 | — | — | US | claimed |
| EP-0281393-B1 | METHOD FOR PRODUCING INDAN DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1993-08-04 | — | — | EP | claimed |
| EP-0215335-B1 | PROCESS FOR PREPARING N-/1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL/-L-ALANYL-L-PROLINE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-11-11 | — | — | EP | claimed |
| EP-0219651-B1 | Inorganic acid salt of N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanylchloride and process for preparing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-10-31 | — | — | EP | claimed |
| US-4835302-A | Method for producing indan derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-30 | — | — | US | claimed |
| EP-0281393-A2 | Method for producing indan derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-09-07 | — | — | EP | claimed |
| US-4716235-A | AMIDATION OF PROLINE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-12-29 | — | — | US | claimed |
| EP-0219651-A1 | Inorganic acid salt of N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanylchloride and process for preparing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-04-29 | — | — | EP | claimed |
| EP-0215335-A2 | Process for preparing N-/1(S)-ethoxycarbonyl-3-phenylpropyl/-L-alanyl-L-proline | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-03-25 | — | — | EP | claimed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10781193-B2 | Process for producing organic compound | TTL, DCLK1, CTH | ACE 2636/4885LMNA 4879/4885ABCB11 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.