Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260882 | 0.78 | MAPT (0.38) | MCL1MAPTALDH1A1L3MBTL1POLB | |
| SCHEMBL6662015 | 0.73 | F2 (0.30) | — | |
| SCHEMBL749191 | 0.69 | MCL1 (0.89) | MCL1MAPTALOX15HTTHBB | |
| SCHEMBL169913 | 0.68 | MCL1 (0.65) | MCL1MAPTALOX15HTTHBB | |
| SCHEMBL11519541 | 0.68 | MCL1 (0.76) | MCL1MAPTALOX15HTTHBB | |
| SCHEMBL600072 | 0.68 | MCL1 (1.00) | MCL1MAPTALOX15HTTHBB | |
| SCHEMBL6575841 | 0.68 | ALDH1A1 (0.33) | MAPTALDH1A1 | |
| SCHEMBL1357104 | 0.67 | MCL1 (0.45) | MCL1MAPTALOX15HTTHBB | |
| SCHEMBL4242992 | 0.64 | MAPT (0.42) | MCL1MAPTALOX15HTTHBB | |
| SCHEMBL15659956 | 0.64 | MCL1 (0.65) | MCL1MAPTALOX15HTTHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263738-B1 | SUBSTITUTED BENZOYLCYCLOHEXENONES | BAYER CROPSCIENCE AG (DE) | 2007-06-27 | — | — | EP | claimed |
| US-7196229-B2 | Benzoylcyclohexenone derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-27 | — | — | US | claimed |
| CN-1268615-C | Substituted benzoylcyclohexenones | BAYER AG (DE) | 2006-08-09 | — | — | CN | claimed |
| US-6969697-B2 | Substituted benzoylcyclohexenones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-29 | — | — | US | claimed |
| US-20040235793-A1 | Benzoylcyclohexenone derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | claimed |
| US-20040002599-A1 | Substituted benzoycyclohexenones | NIHON BAYER AGROCHEM K.K. (JP) | 2004-01-01 | — | — | US | claimed |
| CN-1416422-A | Substituted benzoylcyclohexenones | BAYER AG (DE) | 2003-05-07 | — | — | CN | claimed |
| EP-1263738-A1 | SUBSTITUTED BENZOYLCYCLOHEXENONES | Bayer CropScience AG (DE) | 2002-12-11 | — | — | EP | claimed |
| WO-2001066527-A1 | SUBSTITUTED BENZOYLCYCLOHEXENONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-13 | — | — | WO | claimed |
| CN-107353238-B | Substituted benzoylcyclohexan cyclohexadione compounds or its tautomer, salt, preparation method, Herbicidal combinations and application | 青岛清原化合物有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-107353238-A | Substituted benzoylcyclohexan cyclohexadione compounds or its dynamic isomer, salt, preparation method, Herbicidal combinations and application | 青岛清原化合物有限公司 | 2017-11-17 | — | — | CN | disclosed |
| EP-1392660-B1 | SUBSTITUTED BENZOYLCYCLOHEXENONES AND THEIR USE AS HERBICIDAL AGENTS | BAYER AG (DE) | 2010-08-04 | — | — | EP | disclosed |
| US-7670991-B2 | Substituted benzoylcyclohexenones and their use as herbicidal agents | BAYER CROPSCIENCE AG (DE) | 2010-03-02 | — | — | US | disclosed |
| US-7670991-B2 | Substituted benzoylcyclohexenones and their use as herbicidal agents | BAYER CROPSCIENCE AG (DE) | 2010-03-02 | — | — | US | disclosed |
| WO-2001066527-A1 | SUBSTITUTED BENZOYLCYCLOHEXENONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066527-A1 | SUBSTITUTED BENZOYLCYCLOHEXENONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001040200-A1 | HERBICIDAL 3-(4,5-DIHYDROISOXAZOLE-3-YL)-SUBSTITUTED BENZOYLCYCLOHEXENONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-07 | — | — | WO | disclosed |
| US-6083969-A | 2,3-DIARYLPYRAZOLES FUSED WITH CYCLOALKANES AND CYCLOALKENES, USED AS CYCLOOXYGENASE-2 (COX-2) INHIBITOR | ORTHO-MCNEIL PHARACEUTICAL, INC. (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0673359-A1 | BENZOYLCYCLOHEXENONES, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013619-A1 | BENZOYLCYCLOHEXENONES, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1994-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002599-A1 | Substituted benzoycyclohexenones | CYP1B1, CYP1A1, DDT | MCL1 2214/4885MAPT 4442/4885ALOX15 2681/4885 |
| US-20040235793-A1 | Benzoylcyclohexenone derivatives | CYC1, CYP1B1, CYP1A1 | MCL1 2014/4885MAPT 3560/4885ALOX15 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.