Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985061 | 0.80 | MAPT (0.47) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL10704975 | 0.73 | MAPT (0.41) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL136598 | 0.73 | MAPT (0.41) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL528381 | 0.72 | MAPT (0.40) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL3270605 | 0.72 | MAPT (0.40) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL156512 | 0.72 | MAPT (0.40) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL659656 | 0.72 | GSK3B (0.41) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL993045 | 0.72 | CES1 (0.45) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL363122 | 0.72 | MAPT (0.40) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL2470208 | 0.72 | EPHX1 (0.43) | MAPTALOX15HTTHBBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298976-A1 | Fiber-Reinforced Composition Resin Composition, Adhesive and Sealant | HITACHI, LTD. (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-0426735-B1 | FLUOROPOLYMER BASED COATING COMPOSITION FOR ADHESION DIRECT TO GLASS | PPG INDUSTRIES INC (US) | 1996-01-31 | — | — | EP | disclosed |
| EP-0426735-A1 | FLUOROPOLYMER BASED COATING COMPOSITION FOR ADHESION DIRECT TO GLASS. | PPG INDUSTRIES INC (US) | 1991-05-15 | — | — | EP | disclosed |
| WO-1990001054-A1 | FLUOROPOLYMER BASED COATING COMPOSITION FOR ADHESION DIRECT TO GLASS | PPG INDUSTRIES, INC. (US) | 1990-02-08 | — | — | WO | disclosed |
| US-4879345-A | USING SILANE COUPLIN AGENT | PPG INDUSTRIES, INC. (US) | 1989-11-07 | — | — | US | disclosed |