Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16796041 | 0.75 | ALOX15 (0.35) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL27145902 | 0.73 | LMNA (0.35) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL24554756 | 0.72 | PLAU (0.39) | TSHRALOX15PLAU | |
| Trifluoroacetic Acid SCHEMBL29109271 | 0.70 | PLAU (0.43) | PLAU | |
| SCHEMBL29109244 | 0.69 | KDM4E (0.30) | — | |
| SCHEMBL29109245 | 0.69 | KDM4E (0.30) | — | |
| SCHEMBL2547540 | 0.68 | LMNA (0.57) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15496427 | 0.67 | KDM4E (0.43) | TSHRCYP2C19CYP1A2 | |
| SCHEMBL30525718 | 0.66 | LMNA (0.62) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11343033 | 0.65 | LMNA (0.35) | LMNATSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116848125-A | H4 antagonist compounds | 赫帕雷斯治疗有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-115925721-A | Pyrimidone tricyclic derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-04-07 | — | — | CN | disclosed |