Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525285 | 0.87 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL18770758 | 0.82 | KMT2A (0.51) | MEN1KMT2AALDH1A1GAAGLA | |
| SCHEMBL6200 | 0.82 | KMT2A (0.51) | MEN1KMT2AALDH1A1GAAGLA | |
| SCHEMBL1827043 | 0.81 | CHRM2 (0.41) | LMNAKMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5962066 | 0.81 | GLA (0.52) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL29027430 | 0.81 | KMT2A (0.50) | MEN1KMT2AALDH1A1GAAGLA | |
| Water SCHEMBL659931 | 0.81 | KMT2A (0.50) | MEN1KMT2AALDH1A1GAAGLA | |
| Water SCHEMBL108075 | 0.81 | KMT2A (0.50) | MEN1KMT2AALDH1A1GAAGLA | |
| SCHEMBL5492635 | 0.81 | KMT2A (0.50) | MEN1KMT2AALDH1A1GAAGLA | |
| Ammonia Solution, Strong SCHEMBL1509056 | 0.81 | KMT2A (0.50) | MEN1KMT2AALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251689-B1 | Methods and compositions for obtaining and using biologically active multi-protein complexes | FERRANI-KILE KARIMA (US) | 2015-08-05 | — | — | EP | disclosed |
| US-8470745-B2 | Methods and compositions for obtaining and using biologically active multi-protein complexes | FERRANI-KILE KARIMA (US) | 2013-06-25 | — | — | US | disclosed |
| US-20120157345-A1 | Methods and Compositions for Obtaining and Using Biologically Active Multi-Protein Complexes | FERRANI-KILE KARIMA (US) | 2012-06-21 | — | — | US | disclosed |
| EP-2251689-A1 | Methods and compositions for obtaining and using biologically active multi-protein complexes | Ferrani-Kile, Karima (US) | 2010-11-17 | — | — | EP | disclosed |
| US-20090221098-A1 | METHODS AND COMPOSITIONS FOR OBTAINING AND USING BIOLOGICALLY ACTIVE MULTI-PROTEIN COMPLEXES | FERRANI-KILE, KARIMA | 2009-09-03 | — | — | US | disclosed |
| EP-2002261-A4 | METHODS AND COMPOSITIONS FOR OBTAINING AND USING BIOLOGICALLY ACTIVE MULTI-PROTEIN COMPLEXES | FERRANI-KILE KARIMA (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-2002261-A2 | METHODS AND COMPOSITIONS FOR OBTAINING AND USING BIOLOGICALLY ACTIVE MULTI-PROTEIN COMPLEXES | Ferrani-Kile, Karima (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007115151-A2 | METHODS AND COMPOSITIONS FOR OBTAINING AND USING BIOLOGICALLY ACTIVE MULTI-PROTEIN COMPLEXES | FERRANI-KILE KARIMA (US) | 2007-10-11 | — | — | WO | disclosed |