Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 6/20 | 0.40 |
| ▸ | ARNT | P27540 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 5/20 | 0.34 |
| ▸ | PYGL | P06737 | 8/20 | 0.34 |
| ▸ | METAP2 | P50579 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449427 | 1.00 | EPAS1 (0.40) | EPAS1ARNTFFAR4VEGFAPYGL | |
| SCHEMBL25250060 | 0.91 | ARNT (0.34) | EPAS1ARNT | |
| SCHEMBL24110079 | 0.78 | EPAS1 (0.44) | EPAS1ARNTFFAR4VEGFAPYGL | |
| SCHEMBL29116169 | 0.77 | EPAS1 (0.39) | EPAS1ARNTFFAR4VEGFA | |
| SCHEMBL30373764 | 0.76 | AR (0.36) | EPAS1ARNTVEGFAPYGL | |
| SCHEMBL24110009 | 0.76 | EPAS1 (0.41) | EPAS1ARNTFFAR4VEGFA | |
| SCHEMBL24110056 | 0.76 | EPAS1 (0.43) | EPAS1ARNTFFAR4VEGFA | |
| SCHEMBL30449323 | 0.76 | EPAS1 (0.43) | EPAS1ARNTFFAR4VEGFA | |
| SCHEMBL24109436 | 0.76 | EPAS1 (0.45) | EPAS1ARNTFFAR4VEGFAMETAP2 | |
| SCHEMBL30449307 | 0.76 | EPAS1 (0.45) | EPAS1ARNTFFAR4VEGFAMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884966-A | Bicyclic compounds and uses thereof | 贝达药业股份有限公司 | 2023-03-31 | — | — | CN | disclosed |