Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 11/20 | 0.45 |
| ▸ | ARNT | P27540 | 7/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 5/20 | 0.33 |
| ▸ | METAP2 | P50579 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24109436 | 1.00 | EPAS1 (0.45) | EPAS1ARNTFFAR4VEGFAMETAP2 | |
| SCHEMBL25800592 | 0.91 | EPAS1 (0.40) | EPAS1ARNTVEGFA | |
| SCHEMBL24110079 | 0.88 | EPAS1 (0.44) | EPAS1ARNTFFAR4VEGFAMETAP2 | |
| SCHEMBL24110056 | 0.86 | EPAS1 (0.43) | EPAS1ARNTFFAR4VEGFA | |
| SCHEMBL30449323 | 0.86 | EPAS1 (0.43) | EPAS1ARNTFFAR4VEGFA | |
| SCHEMBL24110081 | 0.85 | EPAS1 (0.53) | EPAS1ARNTVEGFA | |
| SCHEMBL28980671 | 0.85 | EPAS1 (0.53) | EPAS1ARNTVEGFA | |
| SCHEMBL29116096 | 0.85 | EPAS1 (0.53) | EPAS1ARNTVEGFA | |
| SCHEMBL25800760 | 0.85 | ALDH1A1 (0.35) | EPAS1ARNT | |
| SCHEMBL30449352 | 0.84 | EPAS1 (0.42) | EPAS1ARNTFFAR4VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884966-B | Bicyclic compounds and uses thereof | 贝达药业股份有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-115884966-A | Bicyclic compounds and uses thereof | 贝达药业股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-119431335-A | Bicyclic compounds and uses thereof | 贝达药业股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115884966-B | Bicyclic compounds and uses thereof | 贝达药业股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-117126097-A | Bicyclic compounds and uses thereof | 贝达药业股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115884966-A | Bicyclic compounds and uses thereof | 贝达药业股份有限公司 | 2023-03-31 | — | — | CN | disclosed |