Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112493 | 0.93 | PTK6 (0.41) | PTK6EGFRERBB2LCKAURKB | |
| SCHEMBL25450748 | 0.91 | PTK6 (0.39) | PTK6LCKAURKBIRAK4TTK | |
| Iodide SCHEMBL25173515 | 0.91 | PTK6 (0.39) | PTK6LCKAURKB | |
| SCHEMBL25452721 | 0.91 | PTK6 (0.40) | PTK6LCKAURKBTTK | |
| SCHEMBL24112577 | 0.90 | PTK6 (0.38) | PTK6CDK2CDK1LCKAURKB | |
| SCHEMBL22160965 | 0.89 | PTK6 (0.40) | PTK6EGFRERBB2LCKAURKB | |
| SCHEMBL22124671 | 0.88 | PTK6 (0.38) | PTK6EGFRIRAK4 | |
| SCHEMBL30172007 | 0.88 | PTK6 (0.38) | PTK6EGFRIRAK4 | |
| SCHEMBL22124797 | 0.88 | CDK2 (0.36) | PTK6CDK2CDK1IRAK4TTK | |
| SCHEMBL30402648 | 0.86 | PTK6 (0.47) | PTK6EGFRLCKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |
| CN-115916784-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |