Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 15/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25176076 | 0.81 | KDR (0.40) | SYKKDRMEN1NPC1LMNA | |
| SCHEMBL25173790 | 0.77 | TTK (0.48) | SYKAURKA | |
| SCHEMBL28916349 | 0.77 | JAK1 (0.48) | — | |
| SCHEMBL23449232 | 0.76 | CYP46A1 (0.48) | KDRMEN1LMNAMAPTKMT2A | |
| SCHEMBL25173403 | 0.74 | SYK (0.41) | SYK | |
| SCHEMBL2013520 | 0.71 | TRIM33 (0.38) | SYKKDRMAPT | |
| SCHEMBL26436184 | 0.70 | MAPT (0.57) | MEN1NPC1LMNAMAPTRAB9A | |
| SCHEMBL1878367 | 0.70 | KDM4E (0.49) | LMNAMAPTKMT2A | |
| SCHEMBL22123580 | 0.70 | PTK6 (0.40) | SYKKDRLMNAMAPTAURKA | |
| SCHEMBL28961447 | 0.70 | PTK6 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916784-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |