Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | FASN | P49327 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19950938 | 0.84 | GAA (0.43) | TRIM33POLQKDM4EHSD17B10TSHR | |
| SCHEMBL24770169 | 0.84 | MAOB (0.42) | TRIM33MAOBPOLQKDM4EALDH1A1 | |
| SCHEMBL22717449 | 0.84 | KMT2A (0.38) | TRIM33MAOBPOLQKDM4EALDH1A1 | |
| SCHEMBL6918010 | 0.83 | GABRP (0.41) | MAOBFASNKDM4EALDH1A1KDR | |
| SCHEMBL1796361 | 0.82 | MAOB (0.40) | MAOBPOLQFASNNAMPTMCHR1 | |
| SCHEMBL24087313 | 0.81 | NNMT (0.41) | MAOBFASNSYK | |
| SCHEMBL21491461 | 0.81 | MAOB (0.42) | TRIM33MAOBPOLQMAPTKDM4E | |
| SCHEMBL339175 | 0.81 | POLB (0.38) | TRIM33MAOBPOLQKDM4EALDH1A1 | |
| SCHEMBL22842993 | 0.80 | TDP1 (0.45) | TRIM33POLQMAPTKDM4EALDH1A1 | |
| SCHEMBL22836678 | 0.79 | LMNA (0.39) | TRIM33MAOBPOLQNAMPTSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |