Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20237032 | 0.84 | JAK2 (0.37) | LPLLIPGJAK2BTKCXCR2 | |
| SCHEMBL17951295 | 0.84 | JAK2 (0.37) | LPLLIPGJAK2BTKCXCR2 | |
| SCHEMBL30615277 | 0.84 | JAK2 (0.37) | LPLLIPGJAK2BTKCXCR2 | |
| SCHEMBL2586990 | 0.83 | LPL (0.42) | LPLLIPGCXCR2ROCK1 | |
| SCHEMBL30393353 | 0.83 | LPL (0.42) | LPLLIPGCXCR2ROCK1 | |
| SCHEMBL24630498 | 0.82 | LPL (0.46) | LPLLIPGJAK2BTK | |
| SCHEMBL29288003 | 0.82 | JAK2 (0.38) | LPLLIPGJAK2BTKCXCR2 | |
| SCHEMBL17389030 | 0.79 | LIPG (0.39) | LPLLIPGJAK2BTKCXCR2 | |
| SCHEMBL22748266 | 0.78 | LIPG (0.50) | LPLLIPG | |
| SCHEMBL20237129 | 0.78 | LPL (0.33) | LPLLIPGJAK2BTKCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960094-A | Preparation and application of aromatic ring substituted methylamine derivative | 上海璎黎药业有限公司 | 2023-04-14 | — | — | CN | disclosed |