Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984104 | 0.84 | DDB1 (0.35) | ALDH1A1MEN1KMT2AMAPK1GAA | |
| SCHEMBL28984087 | 0.76 | LMNA (0.52) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL31254097 | 0.76 | LMNA (0.52) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL31330812 | 0.71 | KDM4E (0.39) | MEN1KMT2AL3MBTL1LMNAMAPT | |
| SCHEMBL29153133 | 0.68 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL31554609 | 0.68 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL31330879 | 0.68 | TDP1 (0.47) | ALDH1A1MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL28984105 | 0.67 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL30472894 | 0.67 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL13106231 | 0.66 | TDP1 (0.48) | ALDH1A1MAPK1L3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115968293-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-04-14 | — | — | CN | disclosed |