Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30389917 | 1.00 | YTHDC1 (0.46) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL28984093 | 0.92 | YTHDC1 (0.47) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL30389942 | 0.92 | YTHDC1 (0.47) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL17103499 | 0.85 | YTHDC1 (0.49) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL17103497 | 0.85 | YTHDC1 (0.49) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL7921383 | 0.83 | YTHDC1 (0.45) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL3376962 | 0.82 | YTHDC1 (0.58) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL7914854 | 0.80 | YTHDC1 (0.46) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL481563 | 0.78 | YTHDC1 (0.49) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 | |
| SCHEMBL481896 | 0.78 | SLC6A2 (0.49) | YTHDC1SLC6A2SLC6A4KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715903-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 新基公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117561249-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 细胞基因公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117545752-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 细胞基因公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-115968293-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115955979-A | Cereblan binding compounds, compositions thereof, and methods for treatment thereof | 新基公司 | 2023-04-11 | — | — | CN | disclosed |