Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908299 | 0.87 | GRIN2B (0.44) | SIGMAR1GRIN2BALDH1A1 | |
| SCHEMBL7908300 | 0.87 | GRIN2B (0.44) | SIGMAR1GRIN2BALDH1A1 | |
| SCHEMBL15688968 | 0.83 | YTHDC1 (0.49) | YTHDC1SLC6A2SLC6A4KMT2AACKR3 | |
| SCHEMBL28984099 | 0.80 | YTHDC1 (0.46) | YTHDC1SLC6A2SLC6A4KMT2ASIGMAR1 | |
| SCHEMBL30389917 | 0.80 | YTHDC1 (0.46) | YTHDC1SLC6A2SLC6A4KMT2ASIGMAR1 | |
| SCHEMBL7921383 | 0.79 | YTHDC1 (0.45) | YTHDC1SLC6A2SLC6A4KMT2ASIGMAR1 | |
| SCHEMBL3376962 | 0.79 | YTHDC1 (0.58) | YTHDC1SLC6A2SLC6A4KMT2AACKR3 | |
| SCHEMBL28984093 | 0.78 | YTHDC1 (0.47) | YTHDC1SLC6A2SLC6A4KMT2AACKR3 | |
| SCHEMBL30389942 | 0.78 | YTHDC1 (0.47) | YTHDC1SLC6A2SLC6A4KMT2AACKR3 | |
| SCHEMBL1543347 | 0.76 | YTHDC1 (0.51) | YTHDC1SLC6A2SLC6A4KMT2AACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221402-B1 | CORE COMPRISING A MIXTURE OF A DRUG, LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE, MICROCRYSTALLINE CELLULOSE AND BEING COATED WITH A WATER SOLUBLE POLYMER OVERCOATED WITH A SALIVA-INSOLUBLE POLYMER | PFIZER INC. | 2001-04-24 | — | — | US | disclosed |
| US-6211219-B1 | DRUGS, ANALGESICS AND AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0923572-A1 | AMINOCYCLOHEXANE DERIVATIVES AS 5-HT RECEPTOR AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998003504-A1 | AMINOCYCLOHEXANE DERIVATIVES AS 5-HT RECEPTOR AGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1998-01-29 | — | — | WO | disclosed |