Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.53 |
| ▸ | TUBB | P07437 | 3/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22950695 | 0.87 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30734329 | 0.87 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29827249 | 0.87 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28984308 | 0.86 | TUBB1 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28984306 | 0.86 | MTNR1A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28984313 | 0.85 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29827171 | 0.85 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28984314 | 0.85 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28984293 | 0.85 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31238100 | 0.84 | TUBB1 (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535068-B | Pyridine substituted chalcone compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国药科大学 | 2022-07-29 | — | — | CN | disclosed |