Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | PTGES | O14684 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26983565 | 0.79 | CACNA2D1 (0.37) | TSHRHSD17B10DRD2DRD3PPARG | |
| SCHEMBL28667057 | 0.79 | CACNA2D1 (0.37) | TSHRHSD17B10DRD2DRD3PPARG | |
| SCHEMBL24345958 | 0.75 | KMT2A (0.41) | — | |
| SCHEMBL10022420 | 0.74 | CDC7 (0.40) | CDC7CDK2CCR9BRPF1 | |
| SCHEMBL23458895 | 0.73 | BRPF1 (0.39) | CDC7CDK2CCR9BRPF1 | |
| SCHEMBL29965268 | 0.73 | BRPF1 (0.39) | CDC7CDK2CCR9BRPF1 | |
| SCHEMBL21730486 | 0.70 | NR1I2 (0.36) | — | |
| SCHEMBL21783907 | 0.70 | TSHR (0.46) | TSHRHSD17B10CYP19A1GRM2 | |
| SCHEMBL26464630 | 0.68 | PGR (0.37) | TSHRHSD17B10GRM2 | |
| SCHEMBL22664881 | 0.68 | TSHR (0.51) | TSHRHSD17B10CYP19A1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115776890-A | TRPV4 inhibitors as therapeutic agents for eye diseases | 拉夸里亚创药株式会社 | 2023-03-10 | — | — | CN | disclosed |