SCHEMBL2898481

SCHEMBL2898481

Cc1ccc(-c2ccccc2)c(C2(O)CCCCO2)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.38
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
TP53 P04637 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP46A1 Q9Y6A2 2/20 0.34
ESR2 Q92731 1/20 0.34
MAOB P27338 2/20 0.34
PSMB5 P28074 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14087464 0.71 HTR7 (0.51) PDK2MEN1KMT2AALDH1A1
SCHEMBL18649351 0.71 HTR7 (0.41) PDK2ALDH1A1SLC6A2
SCHEMBL109994 0.70 CYP1A2 (0.50) SMN1; SMN2
SCHEMBL14227873 0.70 PDK2 (0.55) PDK2MEN1NPC1TP53RAB9A
SCHEMBL14182746 0.70 PDK2 (0.55) PDK2MEN1NPC1TP53RAB9A
SCHEMBL27851300 0.69 LMNA (0.36) MEN1NPC1TP53RAB9AKMT2A
SCHEMBL7103913 0.68 MEN1 (0.39) MEN1KMT2A
SCHEMBL13355857 0.67 PDK2 (0.47) PDK2HDAC7ALDH1A1ESR2MAOB
SCHEMBL3913576 0.67 POLB (0.39) PDK2PTGDR2SLC6A4SLC6A3
SCHEMBL28002986 0.65 HTR7 (0.36) MEN1KMT2ASMN1; SMN2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2214625-B1 EMULSION COMPOSITION FUJIFILM CORP (JP) 2018-10-03 EP disclosed
US-20100291008-A1 EMULSION COMPOSITION FUJIFILM CORPORATION (JP) 2010-11-18 US disclosed
EP-2214625-A1 EMULSION COMPOSITION FUJIFILM Corporation (JP) 2010-08-11 EP disclosed
WO-2009066799-A1 EMULSION COMPOSITION FUJIFILM CORPORATION (JP) 2009-05-28 WO disclosed