SCHEMBL28985266

SCHEMBL28985266

Cc1ccc(N2CCC(NC(=O)C(=O)c3c[nH]c4ccc(C(C(N)=O)c5ccc6c(c5)OCO6)cc34)C2=O)c(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
B3GAT3 O94766 1/20 0.64
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
CDK4 P11802 3/20 0.34
CCND1 P24385 3/20 0.34
EDNRA P25101 2/20 0.34
RIPK1 Q13546 2/20 0.33
SOS1 Q07889 2/20 0.33
ALDH1A1 P00352 1/20 0.33
F2 P00734 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29504713 0.82 B3GAT3 (0.79) B3GAT3RAB9ACDK4CCND1SOS1
SCHEMBL28984931 0.82 B3GAT3 (0.79) B3GAT3RAB9ACDK4CCND1SOS1
SCHEMBL29504741 0.81 B3GAT3 (0.79) B3GAT3CDK4CCND1
SCHEMBL29504687 0.81 B3GAT3 (0.79) B3GAT3CDK4CCND1
SCHEMBL28984921 0.81 B3GAT3 (0.79) B3GAT3CDK4CCND1
SCHEMBL29504777 0.81 B3GAT3 (0.76) B3GAT3NPC1RAB9ACDK4CCND1
SCHEMBL28984923 0.80 B3GAT3 (0.78) B3GAT3CDK4CCND1ALDH1A1
SCHEMBL28984920 0.80 B3GAT3 (0.75) B3GAT3CDK4CCND1
SCHEMBL28984922 0.80 B3GAT3 (0.85) B3GAT3RAB9ACDK4CCND1RIPK1
SCHEMBL29504658 0.79 B3GAT3 (0.81) B3GAT3NPC1RAB9AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974849-A Indoxyl acetamide derivative, pharmaceutical composition containing indoxyl acetamide derivative and application of indoxyl acetamide derivative 中国药科大学 2023-04-18 CN claimed
CN-115974849-A Indoxyl acetamide derivative, pharmaceutical composition containing indoxyl acetamide derivative and application of indoxyl acetamide derivative 中国药科大学 2023-04-18 CN disclosed