SCHEMBL2898583

SCHEMBL2898583

OCc1ccc(O)cc1F

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TYR P14679 6/20 0.50
CHRNA7 P36544 1/20 0.47
ESR1 P03372 5/20 0.42
ESR2 Q92731 4/20 0.42
ALOX5 P09917 2/20 0.41
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29664506 1.00 TYR (0.50) TYRCHRNA7ESR1ESR2ALOX5
SCHEMBL2767004 0.82 CHRNA7 (0.53) TYRCHRNA7ESR1ESR2ALOX5
SCHEMBL13614613 0.81 TYR (0.50) TYRCHRNA7ESR1ESR2ALOX5
SCHEMBL4678542 0.81 TYR (0.44) TYRCHRNA7ESR1ESR2ALOX5
SCHEMBL647503 0.80 TYR (0.68) TYRALOX5MEN1MAPTKMT2A
SCHEMBL11306662 0.79 TYR (0.48) TYRCHRNA7ESR1ESR2ALOX5
SCHEMBL28757491 0.79 CHRNA7 (0.50) TYRCHRNA7ESR1ESR2ALOX5
SCHEMBL310196 0.79 CHRNA7 (0.50) TYRCHRNA7ESR1ESR2ALOX5
SCHEMBL14446348 0.79 TYR (0.48) TYRCHRNA7ESR1ESR2ALOX5
SCHEMBL4959085 0.79 TYR (0.48) TYRCHRNA7ESR1ESR2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081885-A Substituted phenyl glycoside compound and preparation method and application thereof 浙江大学 2025-06-03 CN claimed
CN-113736349-B Corrosion-resistant epoxy resin coating and preparation method thereof 安徽华辉塑业科技股份有限公司 2022-05-17 CN claimed
CN-113736349-A Corrosion-resistant epoxy resin coating and preparation method thereof 安徽华辉塑业科技股份有限公司 2021-12-03 CN claimed
CN-111162313-A Polymer electrolyte and lithium ion battery 珠海冠宇电池有限公司 2020-05-15 CN claimed
CN-120081885-A Substituted phenyl glycoside compound and preparation method and application thereof 浙江大学 2025-06-03 CN disclosed
CN-119032076-A Novel compounds and uses thereof 株式会社安提昂 2024-11-26 CN disclosed
US-12049444-B2 Monomethyl fumarate precursor drug compounds and pharmaceutical compositions thereof AGATHONBIO CO., LTD. (KR) 2024-07-30 US disclosed
US-20230416460-A1 COMPOUND, RESIN COMPOSITION, RESIN SHEET, RESIN CURED PRODUCT, AND LAMINATED SUBSTRATE TDK CORPORATION (JP) 2023-12-28 US disclosed
WO-2023239171-A1 NOVEL COMPOUND AND USE THEREOF 주식회사 엑티브온 2023-12-14 WO disclosed
CN-116490355-A Compound, resin composition, resin sheet, resin cured product, and laminated substrate TDK株式会社 2023-07-25 CN disclosed
WO-2022209495-A1 COMPOUND, RESIN COMPOSITION, RESIN SHEET, RESIN CURED OBJECT, AND LAMINATED SUBSTRATE TDK株式会社 2022-10-06 WO disclosed
CN-113736349-B Corrosion-resistant epoxy resin coating and preparation method thereof 安徽华辉塑业科技股份有限公司 2022-05-17 CN disclosed
EP-1343775-A2 PIPERAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2003-09-17 EP disclosed
WO-2001020995-A9 COMPOUNDS DIRECTED AGAINST PILUS BIOGENESIS AND ACTIVITY IN PATHOGENIC BACTERIA; METHODS AND COMPOSITIONS FOR SYNTHESIS THEREOF UNIV WASHINGTON (US) 2002-11-14 WO disclosed
US-20020143020-A1 Novel piperazine derivatives VERNALIS RESEARCH LIMITED (GB) 2002-10-03 US disclosed
WO-2002048124-A2 PIPERAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2002-06-20 WO disclosed
WO-2001020995-A1 COMPOUNDS DIRECTED AGAINST PILUS BIOGENESIS AND ACTIVITY IN PATHOGENIC BACTERIA; METHODS AND COMPOSITIONS FOR SYNTHESIS THEREOF WASHINGTON UNIVERSITY (US) 2001-03-29 WO disclosed
CN-1284165-A Method and reagents for quantification of solid-phase reactions using fluorine NMR AVENTISS PHARMACEUTICAL PRODUC (US) 2001-02-14 CN disclosed
EP-1044364-A1 METHOD AND REAGENTS FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR Aventis Pharmaceuticals Products Inc. (US) 2000-10-18 EP disclosed
WO-1999031491-A1 METHOD AND REAGENTS FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020143020-A1 Novel piperazine derivatives CYP4B1, UGT1A1, CYP1B1 TYR 2383/4885CHRNA7 3203/4885ESR1 2206/4885
US-12049444-B2 Monomethyl fumarate precursor drug compounds and pharmaceutical compositions thereof FH, FPGS, FAH TYR 4110/4885CHRNA7 4232/4885ESR1 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.