Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 6/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972328 | 0.83 | TAAR1 (0.54) | CHRNA7TYRHTR2CMEN1CYP3A4 | |
| SCHEMBL30045833 | 0.82 | TYR (0.77) | TYRHTR2CMEN1TP53CYP3A4 | |
| SCHEMBL29664506 | 0.82 | TYR (0.50) | CHRNA7TYRMEN1TP53CYP3A4 | |
| SCHEMBL950883 | 0.82 | TYR (0.77) | TYRHTR2CMEN1TP53CYP3A4 | |
| SCHEMBL2898583 | 0.82 | TYR (0.50) | CHRNA7TYRMEN1TP53CYP3A4 | |
| SCHEMBL2766520 | 0.81 | CHRNA7 (0.51) | CHRNA7TYRMEN1TP53CYP3A4 | |
| SCHEMBL27814767 | 0.81 | TYR (0.55) | CHRNA7TYRMEN1TP53CYP3A4 | |
| SCHEMBL6576435 | 0.81 | CHRNA7 (0.56) | CHRNA7TYRMEN1TP53CYP3A4 | |
| SCHEMBL2335579 | 0.80 | IDO1 (0.50) | HTR2CCA2 | |
| SCHEMBL29696031 | 0.80 | IDO1 (0.50) | HTR2CCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641745-B1 | PROPIONAMIDE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS | ORION CORP (FI) | 2010-04-14 | — | — | EP | disclosed |
| CN-100462353-C | Propionamide derivatives useful as androgen receptor modulators | ORION CORP (FI) | 2009-02-18 | — | — | CN | disclosed |
| US-7390923-B2 | Propionamide derivatives useful as androgen receptor modulators | ORION CORPORATION (FI) | 2008-06-24 | — | — | US | disclosed |
| US-20070123512-A1 | Propionamide derivatives useful as androgen receptor modulators | ORION CORPORATION (FI) | 2007-05-31 | — | — | US | disclosed |
| CN-1812961-A | Propionamide derivatives useful as androgen receptor modulators | ORION CORP (FI) | 2006-08-02 | — | — | CN | disclosed |
| EP-1641745-A1 | PROPIONAMIDE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS | Orion Corporation (FI) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000794-A1 | PROPIONAMIDE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS | ORION CORPORATION (FI) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123512-A1 | Propionamide derivatives useful as androgen receptor modulators | NR5A1, FSHR, GNRHR | CHRNA7 581/4885TYR 2844/4885HTR2C 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.