Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436652 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EKMT2ARAB9AGAA | |
| SCHEMBL289907 | 0.86 | ALDH1A1 (0.59) | APPSMN1; SMN2KDM4EKMT2AHDAC6 | |
| SCHEMBL290136 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EKMT2AHDAC6RAB9A | |
| SCHEMBL290399 | 0.85 | KDM4E (0.48) | SMN1; SMN2KDM4EKMT2ARAB9AGAA | |
| SCHEMBL289399 | 0.81 | HTR2C (0.58) | SMN1; SMN2KDM4EKMT2ARAB9AGAA | |
| SCHEMBL289596 | 0.80 | SMN1; SMN2 (0.74) | SMN1; SMN2KDM4EKMT2ARAB9AGAA | |
| SCHEMBL289408 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2KDM4EKMT2ARAB9AGAA | |
| SCHEMBL289635 | 0.78 | KDM4E (0.57) | APPSMN1; SMN2KDM4EKMT2ARAB9A | |
| SCHEMBL289699 | 0.77 | KDM4E (0.61) | SMN1; SMN2KDM4EKMT2ARAB9AGAA | |
| SCHEMBL289964 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EKMT2AHDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |