Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294538 | 0.94 | POLB (0.41) | KCNH2CACNA1CSCN5AMGLLPOLB | |
| SCHEMBL25253335 | 0.86 | TEAD1 (0.44) | KCNH2CACNA1CSCN5ATEAD1ADAMTS5 | |
| SCHEMBL25290096 | 0.84 | MGLL (0.46) | KCNH2CACNA1CSCN5AMGLLADAMTS5 | |
| SCHEMBL25254799 | 0.84 | MGLL (0.46) | KCNH2CACNA1CSCN5AMGLLADAMTS5 | |
| SCHEMBL25297074 | 0.84 | MGLL (0.46) | KCNH2CACNA1CSCN5AMGLLADAMTS5 | |
| SCHEMBL25254744 | 0.83 | SLC6A4 (0.41) | KCNH2CACNA1CSCN5AMGLLPOLB | |
| SCHEMBL25262919 | 0.79 | ENPP2 (0.39) | KCNH2CACNA1CSCN5AMGLLADAMTS5 | |
| SCHEMBL27215969 | 0.78 | KCNH2 (0.37) | KCNH2CACNA1CSCN5AMGLLPOLB | |
| SCHEMBL25251170 | 0.72 | MGLL (0.42) | MGLLPOLBADAMTS5KMT2ADAO | |
| SCHEMBL25327924 | 0.71 | SCN9A (0.48) | TEAD1EPHX2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989228-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115989228-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | disclosed |