SCHEMBL28986864

SCHEMBL28986864

Cc1c2[c]cccc2nc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.42
BACE1 P56817 1/20 0.42
POLB P06746 2/20 0.41
ALDH1A1 P00352 7/20 0.41
KDM4E B2RXH2 5/20 0.41
HPGD P15428 4/20 0.41
HSD17B10 Q99714 3/20 0.41
MAOA P21397 2/20 0.41
GLA P06280 2/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CHRM2 P08172 1/20 0.41
ADRA2A P08913 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
CHRM1 P11229 1/20 0.41
NQO2 P16083 1/20 0.41
DRD1 P21728 1/20 0.41
ACHE P22303 1/20 0.41
SLC6A2 P23975 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8884724 0.78 KDM4E (0.41) POLBALDH1A1KDM4EHPGDHSD17B10
SCHEMBL7199150 0.78 ACHE (0.61) BACE1POLBALDH1A1KDM4EHPGD
SCHEMBL50940 0.77 GPR3 (0.58) GPR3BACE1POLBALDH1A1KDM4E
SCHEMBL31678400 0.77 GPR3 (0.58) GPR3BACE1POLBALDH1A1KDM4E
SCHEMBL5510470 0.77 PDE10A (0.37) GPR3ALDH1A1KDM4EHPGDHSD17B10
Iodide SCHEMBL10805793 0.75 GPR3 (0.56) GPR3BACE1POLBALDH1A1KDM4E
SCHEMBL1556594 0.72 CYP1A2 (0.41) ALDH1A1KDM4EHPGDHSD17B10MAOA
SCHEMBL8390746 0.70 GPR3 (0.50) GPR3BACE1POLBALDH1A1KDM4E
SCHEMBL15131690 0.69 GPR3 (0.54) GPR3BACE1POLBALDH1A1KDM4E
SCHEMBL28496768 0.68 CYP1A2 (0.33) GPR3HPGDHSD17B10CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112409241-B Organic compound, application thereof and organic electroluminescent device using same 清华大学 2023-04-25 CN disclosed