SCHEMBL28987481

SCHEMBL28987481

CC(C)(C)c1cc(O)c(N)c(C(C)(C)C)c1.NC(=O)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.41
POLB P06746 1/20 0.39
ALDH1A1 P00352 4/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
ALOX15 P16050 3/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
ATP2A2 P16615 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ATP2A3 Q93084 1/20 0.39
EGFR P00533 1/20 0.39
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GABRA1 P14867 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30378905 0.91 POLB (0.46) HSP90AA1POLBALDH1A1MAPTMEN1
SCHEMBL6566674 0.91 POLB (0.46) HSP90AA1POLBALDH1A1MAPTMEN1
Methyl Alcohol SCHEMBL28980879 0.89 POLB (0.45) HSP90AA1POLBALDH1A1MAPTMEN1
SCHEMBL15513927 0.80 ALDH1A1 (0.40) HSP90AA1POLBALDH1A1MAPTMEN1
SCHEMBL139484 0.76 POLB (0.56) HSP90AA1POLBALDH1A1MAPTMEN1
SCHEMBL10796599 0.71 KDM4E (0.42) HSP90AA1POLBALDH1A1KDM4EHSD17B10
SCHEMBL10796211 0.71 KDM4E (0.42) HSP90AA1POLBALDH1A1KDM4EHSD17B10
SCHEMBL14988234 0.71 GLRA3 (0.41) HSP90AA1POLBALDH1A1MAPTGAA
SCHEMBL16147679 0.70 GLRA3 (0.55) HSP90AA1ALDH1A1MAPTALOX15KDM4E
SCHEMBL10796219 0.70 NR5A2 (0.38) HSP90AA1POLBALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003442-A Oxamide derivative and preparation method and application thereof 广西电网有限责任公司电力科学研究院 2023-04-25 CN claimed
CN-116003291-A N, N' -di (3, 5-di-tert-butyl-2-aminophenol hydroxyl) oxamide, preparation method and application thereof 广西电网有限责任公司电力科学研究院 2023-04-25 CN claimed
CN-116003442-A Oxamide derivative and preparation method and application thereof 广西电网有限责任公司电力科学研究院 2023-04-25 CN disclosed
CN-116003291-A N, N' -di (3, 5-di-tert-butyl-2-aminophenol hydroxyl) oxamide, preparation method and application thereof 广西电网有限责任公司电力科学研究院 2023-04-25 CN disclosed