SCHEMBL139484

SCHEMBL139484

CC(C)(C)c1cc(C(C)(C)C)c(N)c(C(C)(C)C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.56
HSP90AA1 P07900 1/20 0.44
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
MAPT P10636 4/20 0.40
GAA P10253 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 6/20 0.38
HTR1D P28221 2/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
PKM P14618 1/20 0.38
RECQL P46063 1/20 0.38
CYP1A2 P05177 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALOX15 P16050 2/20 0.38
ATP2A2 P16615 1/20 0.38
ATP2A3 Q93084 1/20 0.38
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861480 0.89 POLB (0.46) POLBHSP90AA1GABRA1GABRB2MAPT
SCHEMBL27784428 0.87 POLB (0.50) POLBHSP90AA1GABRA1GABRB2MAPT
SCHEMBL10342450 0.87 POLB (0.70) POLBHSP90AA1GABRA1GABRB2MAPT
SCHEMBL9861487 0.85 POLB (0.43) POLBHSP90AA1GABRA1GABRB2MAPT
SCHEMBL8943131 0.85 POLB (0.65) POLBHSP90AA1GABRA1GABRB2MAPT
SCHEMBL6566674 0.84 POLB (0.46) POLBHSP90AA1GABRA1GABRB2MAPT
SCHEMBL30378905 0.84 POLB (0.46) POLBHSP90AA1GABRA1GABRB2MAPT
SCHEMBL9861535 0.82 POLB (0.39) POLBHSP90AA1MAPTKDM4EALDH1A1
Methyl Alcohol SCHEMBL28980879 0.82 POLB (0.45) POLBHSP90AA1GABRA1GABRB2MAPT
SCHEMBL15957594 0.80 POLB (0.43) POLBHSP90AA1MAPTGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 803 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119339933-A Age estimation method based on multidimensional data 中国科学院北京基因组研究所(国家生物信息中心) 2025-01-21 CN claimed
CN-119324053-A Model and index for evaluating aging delaying effect of estrogen replacement therapy and application of model and index 中国科学院北京基因组研究所(国家生物信息中心) 2025-01-17 CN claimed
CN-119285813-A Polymerization inhibitor for polymerization of butadiene unsaturated olefin and preparation method thereof 广东耀辉化工有限公司 2025-01-10 CN claimed
CN-117288848-A Neovascular senile macular degeneration diagnostic marker and application thereof 中南大学湘雅二医院 2023-12-26 CN claimed
CN-116399976-A Method for measuring 2, 6-diisopropylaniline in biodegradable film 贵州省烟草科学研究院 2023-07-07 CN claimed
CN-108250341-B Catalyst system containing metallocene compound and method for catalyzing olefin polymerization by using catalyst system 北京引发科技有限公司 2020-12-11 CN claimed
US-10786805-B2 Cadmium sulfide quantum dots NORTHWESTERN UNIVERSITY (US) 2020-09-29 US claimed
CN-107820338-B Polypyrrole-based antioxidant composite carbon crystal powder 朱红艳 2019-12-20 CN claimed
US-20190225889-A1 METHOD TO EXTRACT BITUMEN FROM OIL SANDS USING AROMATIC AMINES DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-25 US claimed
WO-2018111342-A1 AMINE COMPOSITION FOR STEAM EXTRACTION OF BITUMEN DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-21 WO claimed
WO-2018017221-A1 METHOD TO EXTRACT BITUMEN FROM OIL SANDS USING AROMATIC AMINES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-25 WO claimed
US-20160288106-A1 CADMIUM SULFIDE QUANTUM DOTS UNITED STATES DEPARTMENT OF ENERGY 2016-10-06 US claimed
WO-2016153989-A1 CADMIUM SULFIDE QUANTUM DOTS NORTHWESTERN UNIVERSITY (US) 2016-09-29 WO claimed
US-9161542-B2 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2015-10-20 US claimed
US-20120302611-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2012-11-29 US claimed
WO-2012162595-A2 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2012-11-29 WO claimed
WO-2009143405-A2 SYNTHESIS OF GRAPHENE SHEETS AND NANOPARTICLE COMPOSITES COMPRISING SAME THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2009-11-26 WO claimed
EP-0155686-B1 ORGANOMAGNESIUM SOLUTIONS OF LOW VISCOSITY TEXAS ALKYLS, INC. (US) 1989-06-14 EP claimed
CN-122080074-A Tetradentate ring metal platinum (II) complex and organic electroluminescent device comprising same 2026-05-26 CN disclosed
US-4363333-A NITRIC OXIDE FILTER COMPRISING NITROSO COMPOUND ADSORBED ON ACTIVATED CARBON BRITISH-AMERICAN TOBACCO COMPANY LIMITED (GB) 1982-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120302611-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS PRDX6, PRDX2, PRDX1 POLB 4219/4885HSP90AA1 1086/4885GABRA1 1624/4885
US-10786805-B2 Cadmium sulfide quantum dots AS3MT, TST, SQOR POLB 1676/4885HSP90AA1 2143/4885GABRA1 4548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.