Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | HCK | P08631 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765210 | 0.81 | NOTUM (0.42) | NOTUML3MBTL1HTR6 | |
| SCHEMBL29683534 | 0.81 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1AKT1PIK3CAPIK3CD | |
| SCHEMBL23312247 | 0.81 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1AKT1PIK3CAPIK3CD | |
| SCHEMBL2878376 | 0.79 | NOTUM (0.63) | HSP90AA1HSP90AB1BRD4CREBBPAKT1 | |
| SCHEMBL30763696 | 0.79 | NOTUM (0.63) | HSP90AA1HSP90AB1BRD4CREBBPAKT1 | |
| SCHEMBL18444042 | 0.78 | BRD4 (0.43) | BRD4CREBBPAKT1NOTUMPIM1 | |
| SCHEMBL18443391 | 0.75 | BRD4 (0.43) | HSP90AA1HSP90AB1BRD4CREBBPAKT1 | |
| SCHEMBL25361693 | 0.75 | L3MBTL1 (0.50) | HSP90AA1HSP90AB1BRD4CREBBPAKT1 | |
| SCHEMBL10013786 | 0.75 | L3MBTL1 (0.41) | HSP90AA1HSP90AB1BRD4CREBBPAKT1 | |
| SCHEMBL20782951 | 0.75 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1BRD4PIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322772-A1 | AZAINDOLYLPYRIDONE AND DIAZAINDOLYLPYRIDONE COMPOUNDS | SPRINT BIOSCIENCE AB (SE) | 2023-10-12 | — | — | US | disclosed |
| CN-116589461-A | Azaindolylpyridone compounds and diazaindolylpyridone compounds | 思普瑞特生物科学公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116589462-A | Azaindolylpyridone compounds and diazaindolylpyridone compounds | 思普瑞特生物科学公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111247144-B | Azaindolylpyridone compounds and diazaindolylpyridone compounds | 思普瑞特生物科学公司 | 2023-04-28 | — | — | CN | disclosed |
| US-11498919-B2 | Azaindolylpyridone and diazaindolylpyridone compounds | SPRINT BIOSCIENCE AB (SE) | 2022-11-15 | — | — | US | disclosed |
| EP-4001278-A1 | AZAINDOLYLPYRIDONE AND DIAZAINDOLYLPYRIDONE COMPOUNDS | Sprint Bioscience AB (SE) | 2022-05-25 | — | — | EP | disclosed |
| CN-111247144-A | Azaindolylpyridinone compounds and diazaindolylpyridinone compounds | 思普瑞特生物科学公司 | 2020-06-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322772-A1 | AZAINDOLYLPYRIDONE AND DIAZAINDOLYLPYRIDONE COMPOUNDS | AZI2, IAPP, ZFX | HSP90AA1 4602/4885HSP90AB1 4657/4885BRD4 322/4885 |
| US-11498919-B2 | Azaindolylpyridone and diazaindolylpyridone compounds | AZI2, IAPP, ZFX | HSP90AA1 4602/4885HSP90AB1 4657/4885BRD4 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.