Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 2/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013796 | 0.89 | L3MBTL1 (0.40) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL10013791 | 0.87 | AKT1 (0.37) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL18443391 | 0.76 | BRD4 (0.43) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL424580 | 0.75 | L3MBTL1 (0.48) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL10013761 | 0.75 | AKT1 (0.36) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL28988634 | 0.75 | HSP90AA1 (0.47) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL2878283 | 0.74 | SCN9A (0.44) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL30285064 | 0.74 | KMT2A (0.46) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL3836430 | 0.73 | L3MBTL1 (0.45) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL18487086 | 0.73 | L3MBTL1 (0.45) | L3MBTL1BRD4CREBBPPIM1MARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168833-B2 | Schwartz reagents: methods of in situ generation and use | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-05-01 | — | — | US | disclosed |