Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681887 | 1.00 | POLB (0.43) | POLBKDM4ETDP1MAPTTSHR | |
| SCHEMBL30396306 | 0.76 | KMT2A (0.52) | POLBTDP1MAPTTSHRALDH1A1 | |
| SCHEMBL31681892 | 0.72 | SIRT2 (0.34) | POLBKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28988941 | 0.72 | SIRT2 (0.34) | POLBKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31681891 | 0.72 | SIRT2 (0.34) | POLBKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28988936 | 0.71 | HSD17B10 (0.47) | KDM4ETDP1MAPTTSHRALDH1A1 | |
| SCHEMBL30396310 | 0.71 | HSD17B10 (0.47) | KDM4ETDP1MAPTTSHRALDH1A1 | |
| SCHEMBL11618777 | 0.68 | KMT2A (0.49) | POLBKDM4ETDP1MAPTTSHR | |
| SCHEMBL11507210 | 0.67 | POLB (0.44) | POLBKDM4ETDP1MAPTTSHR | |
| SCHEMBL28466605 | 0.66 | POLB (0.48) | POLBKDM4ETDP1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991698-B | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115991698-A | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2023-04-21 | — | — | CN | disclosed |