Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396310 | 1.00 | HSD17B10 (0.47) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL30396306 | 0.81 | KMT2A (0.52) | LMNAMAPTTDP1KMT2AALDH1A1 | |
| SCHEMBL28988941 | 0.77 | SIRT2 (0.34) | KDM4ELMNACYP1A2MAPTKMT2A | |
| SCHEMBL31681891 | 0.77 | SIRT2 (0.34) | KDM4ELMNACYP1A2MAPTKMT2A | |
| SCHEMBL31681892 | 0.77 | SIRT2 (0.34) | KDM4ELMNACYP1A2MAPTKMT2A | |
| SCHEMBL21774344 | 0.76 | MAPT (0.53) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL28988946 | 0.73 | ALDH1A1 (0.45) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL31681887 | 0.71 | POLB (0.43) | KDM4EMAPTTDP1KMT2AALDH1A1 | |
| SCHEMBL28988933 | 0.71 | POLB (0.43) | KDM4EMAPTTDP1KMT2AALDH1A1 | |
| SCHEMBL28989735 | 0.70 | ALDH1A1 (0.43) | KDM4EMAPTKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613744-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Guangdong Zhongke Medicine Research Ltd. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-115991698-B | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115991698-A | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2023-04-21 | — | — | CN | disclosed |