Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396310 | 0.81 | HSD17B10 (0.47) | KMT2AMAPTALDH1A1TP53TDP1 | |
| SCHEMBL28988936 | 0.81 | HSD17B10 (0.47) | KMT2AMAPTALDH1A1TP53TDP1 | |
| SCHEMBL31681892 | 0.80 | SIRT2 (0.34) | KMT2AMAPTALOX15GAAALDH1A1 | |
| SCHEMBL31681891 | 0.80 | SIRT2 (0.34) | KMT2AMAPTALOX15GAAALDH1A1 | |
| SCHEMBL28988941 | 0.80 | SIRT2 (0.34) | KMT2AMAPTALOX15GAAALDH1A1 | |
| SCHEMBL29279205 | 0.76 | ALDH1A1 (0.54) | KMT2AMAPTGAAALDH1A1MEN1 | |
| SCHEMBL28988933 | 0.76 | POLB (0.43) | KMT2AMAPTGAAALDH1A1TDP1 | |
| SCHEMBL31681887 | 0.76 | POLB (0.43) | KMT2AMAPTGAAALDH1A1TDP1 | |
| SCHEMBL14573716 | 0.75 | KMT2A (0.51) | KMT2AMAPTALOX15GAAALDH1A1 | |
| SCHEMBL22510050 | 0.73 | KMT2A (0.55) | KMT2AMAPTALOX15GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991698-B | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2024-03-29 | — | — | CN | disclosed |