Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681893 | 1.00 | KDM4E (0.40) | KDM4EGAAALDH1A1POLBCYP1A2 | |
| SCHEMBL29413782 | 0.79 | — | — | |
| SCHEMBL29271137 | 0.78 | ALDH1A1 (0.39) | KDM4EGAAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL30912711 | 0.78 | ALDH1A1 (0.39) | KDM4EGAAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL31199041 | 0.78 | MAPT (0.36) | KDM4EALDH1A1CYP1A2ALOX15CYP2C9 | |
| SCHEMBL29413805 | 0.74 | KDR (0.40) | KDM4EALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL28954236 | 0.73 | NPC1 (0.40) | KDM4EALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL29413834 | 0.73 | NPC1 (0.40) | KDM4EALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL29413827 | 0.73 | NPC1 (0.43) | KDM4EGAAALDH1A1POLBCYP1A2 | |
| SCHEMBL29413795 | 0.73 | NPC1 (0.48) | KDM4EALDH1A1POLBCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991698-B | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115991698-A | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2023-04-21 | — | — | CN | disclosed |