Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681893 | 0.78 | KDM4E (0.40) | MAPTCYP1A2KDM4EALDH1A1CYP2C9 | |
| SCHEMBL28989269 | 0.78 | KDM4E (0.40) | MAPTCYP1A2KDM4EALDH1A1CYP2C9 | |
| SCHEMBL7406723 | 0.73 | KDM4E (0.50) | MAPTKDM4EALDH1A1PTGS1MEN1 | |
| SCHEMBL29413782 | 0.72 | — | — | |
| SCHEMBL29271137 | 0.71 | ALDH1A1 (0.39) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30912711 | 0.71 | ALDH1A1 (0.39) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29413855 | 0.70 | FAAH (0.34) | MAPTCYP1A2KDM4EALDH1A1CYP2C9 | |
| SCHEMBL29413812 | 0.70 | MAPT (0.52) | MAPTCYP1A2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL25541972 | 0.70 | PTGS1 (0.47) | MAPTCYP1A2ALDH1A1PTGS1KMT2A | |
| SCHEMBL29413795 | 0.70 | NPC1 (0.48) | MAPTCYP1A2KDM4EALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955469-A | Pyrazole alcohol compound as well as preparation method and application thereof | 安徽中医药大学 | 2024-11-15 | — | — | CN | disclosed |