Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.46 |
| ▸ | CTSK | P43235 | 17/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24981557 | 1.00 | CTSS (0.46) | CTSSCTSKCTSBCTSL | |
| SCHEMBL539422 | 0.80 | ACE (0.50) | CTSSCTSKCTSBCTSL | |
| SCHEMBL3376657 | 0.80 | ACE (0.50) | CTSSCTSKCTSBCTSL | |
| SCHEMBL539351 | 0.79 | KLK5 (0.46) | CTSSCTSKCTSBCTSL | |
| SCHEMBL16065010 | 0.79 | CTSS (0.44) | CTSSCTSKCTSBCTSL | |
| SCHEMBL28989690 | 0.79 | CTSS (0.44) | CTSSCTSKCTSBCTSL | |
| SCHEMBL539352 | 0.79 | KLK5 (0.46) | CTSSCTSKCTSBCTSL | |
| SCHEMBL4245453 | 0.79 | KLK5 (0.46) | CTSSCTSKCTSBCTSL | |
| SCHEMBL31758645 | 0.79 | CTSS (0.41) | CTSSCTSKCTSBCTSL | |
| SCHEMBL2617400 | 0.79 | CTSS (0.65) | CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996923-A | Nitrile derivative as dipeptidyl peptidase 1 inhibitor and application thereof | 四川海思科制药有限公司 | 2023-04-21 | — | — | CN | disclosed |