Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30242664 | 0.84 | DNMT3A (0.38) | DNMT3AAVPR1BCYP4F2CYP4A11SIGMAR1 | |
| SCHEMBL24012720 | 0.84 | DNMT3A (0.38) | DNMT3AAVPR1BCYP4F2CYP4A11SIGMAR1 | |
| SCHEMBL30242637 | 0.80 | CMKLR1 (0.35) | DNMT3AAVPR1BCYP4F2CYP4A11SIGMAR1 | |
| SCHEMBL24012969 | 0.80 | CMKLR1 (0.35) | DNMT3AAVPR1BCYP4F2CYP4A11SIGMAR1 | |
| SCHEMBL30242538 | 0.80 | CYP4F2 (0.35) | DNMT3AAVPR1BCYP4F2CYP4A11RXRA | |
| SCHEMBL24012616 | 0.80 | CYP4F2 (0.35) | DNMT3AAVPR1BCYP4F2CYP4A11RXRA | |
| SCHEMBL24012651 | 0.80 | LSS (0.38) | AVPR1BCYP4F2CYP4A11HTR1AHTR1D | |
| SCHEMBL24012649 | 0.80 | CYP4F2 (0.40) | AVPR1BCYP4F2CYP4A11SIGMAR1RXRA | |
| SCHEMBL5648303 | 0.78 | RXRA (0.32) | DNMT3ARXRARXRBRXRGATR | |
| SCHEMBL24013099 | 0.78 | CMKLR1 (0.37) | CYP4F2CYP4A11RETHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996932-A | New macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2023-04-21 | — | — | CN | disclosed |