Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 13/20 | 0.82 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | MGAM | O43451 | 1/20 | 0.58 |
| ▸ | TOP2A | P11388 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.50 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.50 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.50 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.50 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.50 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.50 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.50 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30346445 | 1.00 | MAOA (0.82) | MAOAACHEMAOBMGAMTOP2A | |
| SCHEMBL7931361 | 0.90 | MAOA (1.00) | MAOAACHEMAOBMGAMTOP2A | |
| SCHEMBL30346290 | 0.84 | MAOA (0.83) | MAOAACHEMAOBMGAMTOP2A | |
| SCHEMBL5348538 | 0.84 | MAOA (0.83) | MAOAACHEMAOBMGAMTOP2A | |
| SCHEMBL8484364 | 0.81 | MAOA (1.00) | MAOAACHEMAOBMGAMTOP2A | |
| SCHEMBL30346412 | 0.81 | MAOA (0.79) | MAOAACHEMAOBTOP2AKDM4E | |
| SCHEMBL31237273 | 0.80 | MAOA (1.00) | MAOAACHEMAOBMGAMKDM4E | |
| SCHEMBL31238429 | 0.80 | MAOA (1.00) | MAOAACHEMAOBMGAMKDM4E | |
| SCHEMBL27976593 | 0.80 | MAOA (1.00) | MAOAACHEMAOBMGAMKDM4E | |
| SCHEMBL22325695 | 0.79 | MAOA (0.81) | MAOAACHEMAOBTOP2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369599-B | Xanthone compound and preparation method and application thereof | 广州医科大学 | 2023-03-24 | — | — | CN | disclosed |