SCHEMBL7931361

SCHEMBL7931361

COc1cc(O)c2c(=O)c3cccc(OC)c3oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 13/20 1.00
ACHE P22303 1/20 0.81
MAOB P27338 1/20 0.81
MGAM O43451 2/20 0.70
TOP2A P11388 4/20 0.63
ATP1A1 P05023 1/20 0.58
ATP1B1 P05026 1/20 0.58
ATP1A3 P13637 1/20 0.58
ATP1B2 P14415 1/20 0.58
ATP1A2 P50993 1/20 0.58
ATP1B3 P54709 1/20 0.58
FXYD2 P54710 1/20 0.58
ATP1A4 Q13733 1/20 0.58
KDM4E B2RXH2 1/20 0.57
NPC1 O15118 1/20 0.57
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
RAB9A P51151 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5348538 0.91 MAOA (0.83) MAOAACHEMAOBMGAMTOP2A
SCHEMBL30346290 0.91 MAOA (0.83) MAOAACHEMAOBMGAMTOP2A
SCHEMBL30346445 0.90 MAOA (0.82) MAOAACHEMAOBMGAMTOP2A
SCHEMBL28990263 0.90 MAOA (0.82) MAOAACHEMAOBMGAMTOP2A
SCHEMBL27976593 0.90 MAOA (1.00) MAOAACHEMAOBMGAMATP1A1
SCHEMBL31237273 0.90 MAOA (1.00) MAOAACHEMAOBMGAMATP1A1
SCHEMBL31238429 0.90 MAOA (1.00) MAOAACHEMAOBMGAMATP1A1
SCHEMBL8484364 0.88 MAOA (1.00) MAOAACHEMAOBMGAMTOP2A
SCHEMBL5349187 0.86 MAOA (0.76) MAOAACHEMAOBMGAMTOP2A
SCHEMBL14466970 0.86 MAOA (0.76) MAOAACHEMAOBMGAMTOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2950832-B1 COATING FOR SUBSTRATE GORE & ASS (US) 2018-08-01 EP disclosed
US-9272075-B2 Coating for substrate W.L. GORE & ASSOCIATES, INC. (US) 2016-03-01 US disclosed
EP-2950832-A1 COATING FOR SUBSTRATE W. L. Gore & Associates, Inc. (US) 2015-12-09 EP disclosed
CN-104936626-A Coating for substrate GORE & ASS 2015-09-23 CN disclosed
WO-2014118382-A1 COATING FOR SUBSTRATE W. L. GORE & ASSOCIATES, INC. (US) 2014-08-07 WO disclosed
US-20140221522-A1 COATING FOR SUBSTRATE W. L. GORE & ASSOCIATES, INC. 2014-08-07 US disclosed
US-6224906-B1 STABLE, FREE-FLOWING POWDER NATREON INC. 2001-05-01 US disclosed