Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AOC2 | O75106 | 5/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990330 | 0.79 | TYRO3 (0.39) | PPARG | |
| SCHEMBL28990335 | 0.79 | HRH3 (0.41) | GAAMEN1KMT2AKDM4E | |
| SCHEMBL30373630 | 0.79 | TYRO3 (0.39) | PPARG | |
| SCHEMBL31185920 | 0.77 | ANPEP (0.47) | MAOBMAOAKLK5SIRT1PPARG | |
| SCHEMBL3345089 | 0.77 | MAOB (0.43) | MAOBMAOAKLK5SIRT1PPARG | |
| SCHEMBL4467512 | 0.77 | ANPEP (0.47) | MAOBMAOAKLK5SIRT1PPARG | |
| SCHEMBL8927781 | 0.77 | ACHE (0.48) | MAOBMAOAKLK5SIRT1PPARG | |
| SCHEMBL15147104 | 0.77 | ACHE (0.48) | MAOBMAOAKLK5SIRT1PPARG | |
| SCHEMBL2885515 | 0.77 | MAOA (0.43) | MAOBMAOAKLK5SIRT1PPARG | |
| SCHEMBL29629339 | 0.77 | ACHE (0.48) | MAOBMAOAKLK5SIRT1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991695-B | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-115991695-A | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-21 | — | — | CN | disclosed |