Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990301 | 0.87 | PTPN1 (0.64) | PTPN1PTPN2SMN1; SMN2ALDH1A1NPC1 | |
| Formylchromone SCHEMBL30783534 | 0.78 | PTPN1 (1.00) | PTPN1PTPN2SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL30715535 | 0.78 | CYP11B1 (0.54) | PTPN1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28990297 | 0.78 | CYP11B1 (0.54) | PTPN1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28988609 | 0.77 | PTPN1 (0.59) | PTPN1PTPN2SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL25567716 | 0.77 | MAOB (0.56) | PTPN1SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL28990341 | 0.75 | ALDH1A1 (0.47) | PTPN1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28990327 | 0.75 | ALDH1A1 (0.47) | PTPN1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL12181816 | 0.73 | PTPN1 (0.54) | PTPN1PTPN2SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL10610131 | 0.71 | MAOA (0.64) | PTPN1PTPN2SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991695-B | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-115991695-A | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-21 | — | — | CN | disclosed |