Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990751 | 1.00 | SIGMAR1 (0.41) | SIGMAR1AOC3SLC6A4ADRB1HTR2A | |
| SCHEMBL28990605 | 0.91 | AOC3 (0.42) | SIGMAR1AOC3ADRB1HTR2AHTR2B | |
| SCHEMBL28990773 | 0.91 | AOC3 (0.42) | SIGMAR1AOC3ADRB1HTR2AHTR2B | |
| SCHEMBL28990573 | 0.89 | SIGMAR1 (0.38) | SIGMAR1AOC3ADRB1HTR2AHTR2B | |
| SCHEMBL28990762 | 0.89 | SIGMAR1 (0.38) | SIGMAR1AOC3ADRB1HTR2AHTR2B | |
| SCHEMBL28990756 | 0.84 | SIGMAR1 (0.40) | SIGMAR1 | |
| SCHEMBL28990748 | 0.84 | SIGMAR1 (0.40) | SIGMAR1 | |
| SCHEMBL28990779 | 0.83 | AOC3 (0.38) | SIGMAR1AOC3ADRB1HTR2AHTR2B | |
| SCHEMBL28990520 | 0.83 | AOC3 (0.38) | SIGMAR1AOC3ADRB1HTR2AHTR2B | |
| SCHEMBL28990760 | 0.83 | AOC3 (0.38) | SIGMAR1AOC3ADRB1HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |