SCHEMBL28990779

SCHEMBL28990779

COCOCC[C@H](OC(N)=O)c1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.38
ADRB1 P08588 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2B P41595 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28990520 1.00 AOC3 (0.38) AOC3ADRB1HTR2AHTR2BSIGMAR1
SCHEMBL28990760 1.00 AOC3 (0.38) AOC3ADRB1HTR2AHTR2BSIGMAR1
SCHEMBL28990762 0.92 SIGMAR1 (0.38) AOC3ADRB1HTR2AHTR2BSIGMAR1
SCHEMBL28990573 0.92 SIGMAR1 (0.38) AOC3ADRB1HTR2AHTR2BSIGMAR1
SCHEMBL28990605 0.89 AOC3 (0.42) AOC3ADRB1HTR2AHTR2BSIGMAR1
SCHEMBL28990773 0.89 AOC3 (0.42) AOC3ADRB1HTR2AHTR2BSIGMAR1
SCHEMBL28990751 0.83 SIGMAR1 (0.41) AOC3ADRB1HTR2AHTR2BSIGMAR1
SCHEMBL28990664 0.83 SIGMAR1 (0.41) AOC3ADRB1HTR2AHTR2BSIGMAR1
SCHEMBL28990735 0.81 AOC3 (0.36) AOC3
SCHEMBL28990718 0.81 AOC3 (0.36) AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111419830-B Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes 比皮艾思药物研发有限公司 2024-01-30 CN disclosed
CN-115996905-A Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases 生物药品解决方案有限公司 2023-04-21 CN disclosed