Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990639 | 1.00 | HPGD (0.37) | HPGDCASP1P2RX7TSHRL3MBTL1 | |
| SCHEMBL28990667 | 0.92 | CASP1 (0.38) | HPGDCASP1P2RX7TSHRAOC3 | |
| SCHEMBL28990632 | 0.92 | CASP1 (0.38) | HPGDCASP1P2RX7TSHRAOC3 | |
| SCHEMBL28990782 | 0.90 | AVPR2 (0.35) | CASP1L3MBTL1AOC3ATMOPRM1 | |
| SCHEMBL28990727 | 0.90 | AVPR2 (0.35) | CASP1L3MBTL1AOC3ATMOPRM1 | |
| SCHEMBL28990608 | 0.86 | CASP1 (0.40) | HPGDCASP1P2RX7TSHRL3MBTL1 | |
| SCHEMBL28990789 | 0.85 | HPGD (0.40) | HPGDP2RX7TSHRALDH1A1GLA | |
| SCHEMBL28990701 | 0.85 | MAPT (0.37) | CASP1AOC3AVPR2AVPR1A | |
| SCHEMBL28990747 | 0.85 | MAPT (0.37) | CASP1AOC3AVPR2AVPR1A | |
| SCHEMBL28990596 | 0.84 | AVPR2 (0.35) | CASP1P2RX7AOC3ATMAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |