Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30076384 | 1.00 | KDM4E (0.44) | KDM4ENPC1LMNARAB9APDE4A | |
| SCHEMBL23081412 | 0.91 | P2RX7 (0.39) | KDM4ENPC1LMNARAB9APDE4A | |
| SCHEMBL25974658 | 0.91 | P2RX7 (0.39) | KDM4ENPC1LMNARAB9APDE4A | |
| SCHEMBL20477230 | 0.89 | CYP19A1 (0.50) | KDM4ELMNARAB9APDE4APDE4B | |
| SCHEMBL20477228 | 0.89 | CYP19A1 (0.50) | KDM4ELMNARAB9APDE4APDE4B | |
| SCHEMBL23081613 | 0.87 | P2RX7 (0.35) | KDM4ENPC1LMNARAB9APDE4A | |
| SCHEMBL30121872 | 0.87 | ALDH1A1 (0.41) | NPC1LMNARAB9AALDH1A1ELANE | |
| SCHEMBL23070389 | 0.87 | TSHR (0.39) | KDM4ENPC1LMNARAB9AELANE | |
| SCHEMBL23070390 | 0.87 | TSHR (0.39) | KDM4ENPC1LMNARAB9AELANE | |
| SCHEMBL28991056 | 0.87 | KDM4E (0.47) | KDM4ENPC1LMNARAB9APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867557-B | Azepine condensed ring compound and medical application thereof | 中国医药研究开发中心有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115867557-A | Azepine fused ring compounds and medical application thereof | 中国医药研究开发中心有限公司 | 2023-03-28 | — | — | CN | disclosed |
| WO-2022237890-A1 | AZEPINE-TYPE FUSED RING COMPOUND AND PHARMACEUTICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2022-11-17 | — | — | WO | disclosed |