Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 8/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | PNLIP | P16233 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30386562 | 1.00 | STING1 (0.53) | STING1EPHX2PNLIPIGF1RTRPV1 | |
| SCHEMBL30885398 | 0.86 | STING1 (0.72) | STING1EPHX2IGF1RTRPV1IDH1 | |
| SCHEMBL28991890 | 0.81 | STING1 (0.61) | STING1EPHX2IGF1RTRPV1 | |
| SCHEMBL30387020 | 0.81 | STING1 (0.61) | STING1EPHX2IGF1RTRPV1 | |
| SCHEMBL30387260 | 0.81 | STING1 (0.64) | STING1EPHX2IGF1RTRPV1IDH1 | |
| SCHEMBL28991251 | 0.81 | STING1 (0.64) | STING1EPHX2IGF1RTRPV1IDH1 | |
| SCHEMBL28991900 | 0.81 | STING1 (0.64) | STING1EPHX2IGF1RTRPV1IDH1 | |
| SCHEMBL30387344 | 0.81 | STING1 (0.64) | STING1EPHX2IGF1RTRPV1IDH1 | |
| SCHEMBL30885411 | 0.80 | STING1 (0.70) | STING1EPHX2RAB9A | |
| SCHEMBL30885401 | 0.80 | STING1 (0.46) | STING1EPHX2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023321-A | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2023-04-28 | — | — | CN | disclosed |