Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 12/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28991301 | 1.00 | STING1 (0.57) | STING1GRIK1NHERF1KCNK2KCNK10 | |
| SCHEMBL30885397 | 0.94 | STING1 (0.51) | STING1GRIK1NHERF1KCNK2KCNK10 | |
| SCHEMBL30885459 | 0.94 | STING1 (0.51) | STING1GRIK1NHERF1KCNK2KCNK10 | |
| SCHEMBL30885448 | 0.91 | STING1 (0.57) | STING1GRIK1KCNK2KCNK10KIF11 | |
| SCHEMBL30885386 | 0.88 | STING1 (0.58) | STING1KCNK2KIF11 | |
| SCHEMBL30885389 | 0.87 | STING1 (0.57) | STING1KCNK2KCNK10KIF11 | |
| SCHEMBL30885429 | 0.87 | STING1 (0.51) | STING1KIF11 | |
| SCHEMBL30885400 | 0.86 | STING1 (0.47) | STING1GRIK1 | |
| SCHEMBL28991278 | 0.86 | STING1 (0.62) | STING1GRIK1NHERF1 | |
| SCHEMBL30387362 | 0.86 | STING1 (0.62) | STING1GRIK1NHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023321-B | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-116023321-A | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2023-04-28 | — | — | CN | disclosed |