Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GOT1 | P17174 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28991333 | 1.00 | STING1 (0.56) | STING1GRIK1SNCANHERF1CNR1 | |
| SCHEMBL30885411 | 0.88 | STING1 (0.70) | STING1GRIK1SNCANHERF1GOT1 | |
| SCHEMBL30387362 | 0.82 | STING1 (0.62) | STING1GRIK1SNCANHERF1GOT1 | |
| SCHEMBL28991278 | 0.82 | STING1 (0.62) | STING1GRIK1SNCANHERF1GOT1 | |
| SCHEMBL28991251 | 0.82 | STING1 (0.64) | STING1SNCANHERF1CNR1P2RY1 | |
| SCHEMBL30387260 | 0.82 | STING1 (0.64) | STING1SNCANHERF1CNR1P2RY1 | |
| SCHEMBL30885398 | 0.81 | STING1 (0.72) | STING1P2RY1GOT1TRPV1 | |
| SCHEMBL23207649 | 0.80 | STING1 (0.65) | STING1GRIK1CNR1GOT1MAPT | |
| SCHEMBL30387020 | 0.80 | STING1 (0.61) | STING1GRIK1NHERF1GOT1TRPV1 | |
| SCHEMBL28991890 | 0.80 | STING1 (0.61) | STING1GRIK1NHERF1GOT1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023321-B | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-116023321-A | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2023-04-28 | — | — | CN | disclosed |