SCHEMBL28991973

SCHEMBL28991973

O=[PH](O)OCCCCc1ccc(Br)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.42
HTR2A P28223 1/20 0.42
HSP90AA1 P07900 1/20 0.38
IDO1 P14902 2/20 0.37
LTB4R Q15722 1/20 0.36
LTB4R2 Q9NPC1 1/20 0.36
FFAR1 O14842 2/20 0.36
HMOX1 P09601 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
PLAAT3 P53816 1/20 0.36
PLAAT5 Q96KN8 1/20 0.36
PLAAT2 Q9NWW9 1/20 0.36
PLAAT4 Q9UL19 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
POLB P06746 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27190586 0.87 TAAR1 (0.47) TAAR1HTR2AIDO1FFAR1FFAR4
SCHEMBL4413671 0.86 TAAR1 (0.45) TAAR1HTR2AHSP90AA1IDO1LTB4R
SCHEMBL7434838 0.82 FFAR1 (0.49) IDO1FFAR1
SCHEMBL28784998 0.81 MAPT (0.50) IDO1FFAR1
SCHEMBL27522937 0.81 MAPT (0.50) IDO1FFAR1
SCHEMBL4415096 0.80 TAAR1 (0.47) TAAR1HTR2AIDO1FFAR1HMOX1
SCHEMBL28170101 0.79 MAPT (0.49) IDO1FFAR1
SCHEMBL30473285 0.79 THRB (0.37) FFAR1MEN1KMT2A
SCHEMBL17061044 0.77 LMNA (0.53) HTR2AIDO1FFAR1
SCHEMBL4938371 0.76 IDO1 (0.48) TAAR1HTR2AIDO1FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041392-A Compound containing phosphate group, preparation method and application thereof 中国科学院长春应用化学研究所 2023-05-02 CN disclosed