Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.36 |
| ▸ | JAK1 | P23458 | 4/20 | 0.36 |
| ▸ | JAK3 | P52333 | 4/20 | 0.36 |
| ▸ | TYK2 | P29597 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28991986 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL29186840 | 0.79 | — | — | |
| Formaldehyde SCHEMBL7383866 | 0.75 | JAK2 (0.42) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL4718556 | 0.74 | JAK2 (0.38) | JAK2JAK1JAK3TYK2 | |
| Bromoethane SCHEMBL28429545 | 0.71 | JAK2 (0.36) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL96570 | 0.69 | — | — | |
| 1,3-Propanediol SCHEMBL15299981 | 0.69 | JAK2 (0.36) | JAK2JAK1JAK3TYK2 | |
| Bromide SCHEMBL31349334 | 0.67 | — | — | |
| SCHEMBL29290488 | 0.67 | — | — | |
| Fluoride SCHEMBL28353010 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221877-B1 | IN PARTICULAR BOVINE TRICHOMONIASIS AND GIARDIASIS | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-04-24 | — | — | US | disclosed |