Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18083628 | 0.89 | BRD4 (0.41) | BRD4TSHRGLAEPHX2PDE4A | |
| SCHEMBL7888405 | 0.89 | BRD4 (0.41) | BRD4TSHRGLAEPHX2PDE4A | |
| SCHEMBL30772713 | 0.84 | TSHR (0.40) | TSHRGLAEPHX2PDE4APDE4B | |
| SCHEMBL6615728 | 0.83 | POLB (0.41) | TSHRLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL321972 | 0.81 | — | — | |
| SCHEMBL20835098 | 0.79 | BRD4 (0.34) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12986559 | 0.79 | LMNA (0.35) | BRD4LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL868953 | 0.78 | BRD4 (0.47) | BRD4TSHREPHX2HPGDPOLB | |
| SCHEMBL3631878 | 0.78 | — | — | |
| SCHEMBL12081534 | 0.77 | SLC6A12 (0.39) | BRD4HPGDLMNAPOLBNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-110300791-B | Quantum dot dispersion, self-luminous photosensitive resin composition, color filter, and image display device | 东友精细化工有限公司 | 2023-03-31 | — | — | CN | disclosed |