Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289397 | 0.86 | LMNA (0.54) | KDM4ERAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL289595 | 0.86 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4ERAB9AGAAKMT2A | |
| SCHEMBL289881 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4ERAB9AGAAKMT2A | |
| SCHEMBL290011 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ERAB9AGAAKMT2A | |
| SCHEMBL290470 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ERAB9AGAAKMT2A | |
| SCHEMBL290016 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4ERAB9AGAAKMT2A | |
| SCHEMBL290238 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4ERAB9AGAAKMT2A | |
| SCHEMBL290152 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4ERAB9AGAAKMT2A | |
| SCHEMBL4659871 | 0.76 | KDM1A (0.56) | RAB9AKMT2ANPC1KDM1AIKBKB | |
| SCHEMBL290000 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4ERAB9AGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |