SCHEMBL28993183

SCHEMBL28993183

CC(C)(O)C(C)(C)Oc1ccc([Si](C)(C)C)cc1.OBO

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
PPARA Q07869 3/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
PPARG P37231 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27920698 0.72 CA1 (0.50) CYP3A4MAPTACHE
SCHEMBL17101177 0.71 GAA (0.44) MEN1CYP1A2CYP3A4MAPTKMT2A
SCHEMBL17312043 0.71 CA1 (0.48) CYP3A4MAPTACHE
SCHEMBL27862358 0.71 ALDH1A1 (0.45) MEN1CYP3A4MAPTKMT2A
SCHEMBL11877180 0.70 PPARA (0.65) PPARAMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL1022162 0.69 CA4 (0.39) NR1H2PPARAMEN1CYP1A2CYP3A4
SCHEMBL27617060 0.69 CA4 (0.39) NR1H2PPARAMEN1CYP1A2CYP3A4
Boric Acid SCHEMBL28233693 0.68 ACHE (0.38) PPARAMEN1CYP1A2CYP3A4CYP2D6
Boric Acid SCHEMBL27908262 0.67 CYP1A2 (0.36) CYP1A2CYP3A4CYP2D6CYP2C19
Boric Acid SCHEMBL28032687 0.67 MEN1 (0.31) PPARAMEN1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874244-A Preparation method of arylboronic acid ester or alkyl boronate compound 中国科学院兰州化学物理研究所 2022-08-09 CN disclosed